Background: Mutations in the LPL gene cause familial lipoprotein lipase deficiency. Symptoms of familial LPL deficiency usually begin in childhood and include abdominal pain, acute and recurrent ...

A deficiency in GPIHBP1 prevents lipoprotein lipase from reaching the capillary lumen. Patients with GPIHBP1 deficiency have low plasma levels of lipoprotein lipase, impaired intravascular ...

Low-density lipoprotein (LDL), the "bad cholesterol" that doctors consider a sign of potential heart disease, is merely a marker of a diet lacking all of the essential amino acids, says University ...

New Rochelle, NY, May 1, 2018--During the first 18 months after treatment with ali-pogene tiparvovec, a gene therapy recently approved in Europe to treat lipoprotein lipase deficiency (LPLD), the ...

In a study published September 17 in Neuron, Guojun Bu at the Mayo Clinic in Jacksonville, Florida, and colleagues report that a drop in the expression of the low-density lipoprotein receptor ...

This means the body is unable to process cholesterol into high-density lipoprotein (HDL), or good ... a related condition known as familial HDL deficiency. If both parents are carriers for Tangier ...

Lipoprotein (a) is a low-density lipoprotein that transports cholesterol in the blood. The lipoprotein (a) test — or Lp(a) test — determines the level of this lipoprotein in the blood, and its ...

The article "Gene Therapy in Lipoprotein Lipase Deficiency (LPLD): Case Report on the First Patient Treated with Alipogene Tiparvovec under Daily Practice Conditions" was coauthored by Ursula ...