Here we apply it to biological data, using three well-characterized mass cytometry and single-cell RNA sequencing datasets. Comparing the performance of UMAP with five other tools, we find that ...

However, traditional bulk-labeling techniques are incompetent to dissect heterogeneity within cell population, while the new single-cell lineage tracing methods invented in the last decade can ...

They compared their results to previously published H3K27me3 scCUT&Tag profiles of a leukemia cell line (K562) and hESCs. Using uniform manifold approximation (UMAP) embedding and ArchR, a software ...