Within a few years after their introduction into widespread clinical use, three major classes of inhaled ... early research on anesthesia to focus on nonspecific biophysical mechanisms.

Previous studies have suggested that inhaled general anesthetics such as sevoflurane ... little is known about interaction sites or the mechanism of action. Penn's Roderic Eckenhoff, MD, vice ...

In 40 patients undergoing ophthalmic surgery using either inhaled sevoflurane plus nitrous oxide or i.v. propofol for induction, satisfaction with induction of anesthesia was assessed afterward by ...

Anesthetics have been used in surgical procedures for more than 150 years, but the mechanisms by which inhaled anesthesia ... of anesthetics to block the action of PSD scaffolding proteins ...

Less is known about the mechanism of action of general anesthetics compared to locals, despite their use for more than 150 years. The most commonly used general anesthetic agents are administered ...

"Beyond suggesting a mechanism of anesthetic action, this discovery is of great clinical importance because it suggests that brain states under general anesthesia can be monitored using the EEG on ...

The anesthetic plan involves general endotracheal anesthesia with intravenous induction, an inhaled anesthetic for ... lowest solubility in brain (site of action), fat, and muscle tissues, and ...

The most commonly used such agents are inhaled, and their chemical ... so probably no single molecular mechanism of action exists for all anesthetics. Thus, the simple answer to the question ...

Previous research has suggested that an inhaled anesthetic ... and its underlying mechanisms," says Xie. "We hope this work will lead to more research on anesthesia, tau proteins, and Alzheimer's ...

Clinical studies have demonstrated that a single sub-anesthetic dose of the dissociative ... Here we review hypotheses for the mechanism of action of ketamine as an antidepressant, including ...