Within a few years after their introduction into widespread clinical use, three major classes of inhaled ... early research on anesthesia to focus on nonspecific biophysical mechanisms.

The anesthetic plan involves general endotracheal anesthesia with intravenous induction, an inhaled anesthetic for ... lowest solubility in brain (site of action), fat, and muscle tissues, and ...

Previous studies have suggested that inhaled general anesthetics such as sevoflurane ... little is known about interaction sites or the mechanism of action. Penn's Roderic Eckenhoff, MD, vice ...

Less is known about the mechanism of action of general anesthetics compared to locals, despite their use for more than 150 years. The most commonly used general anesthetic agents are administered ...

In 40 patients undergoing ophthalmic surgery using either inhaled sevoflurane plus nitrous oxide or i.v. propofol for induction, satisfaction with induction of anesthesia was assessed afterward by ...

Anesthetics have been used in surgical procedures for more than 150 years, but the mechanisms by which inhaled anesthesia ... of anesthetics to block the action of PSD scaffolding proteins ...

Antiinflammatory homeostatic mechanisms reverse these processes as ... as is the case with inhaled glucocorticoids. 67,92 The potency of glucocorticoids as inhibitors of diverse inflammatory ...

spectroscopic technique to explain the detailed molecular mechanism behind the aggregation of amyloid β (Aβ) peptide due to various anesthetics. Inhaled anesthetics commonly used in surgery are ...

"Beyond suggesting a mechanism of anesthetic action, this discovery is of great clinical importance because it suggests that brain states under general anesthesia can be monitored using the EEG on ...

Clinical studies have demonstrated that a single sub-anesthetic dose of the dissociative ... Here we review hypotheses for the mechanism of action of ketamine as an antidepressant, including ...

The most commonly used such agents are inhaled, and their chemical ... so probably no single molecular mechanism of action exists for all anesthetics. Thus, the simple answer to the question ...

Aridis Pharmaceuticals Inc's (NASDAQ: ARDS) inhaled treatment of its fully ... neutralizes coronaviruses using a distinct mechanism of action: inhibition of viral fusion and entry into human ...