To estimate the occupancy of A 1 adenosine receptors by caffeine, the distribution volume at the baseline period of the PET scan was compared with the distribution volume after caffeine ...

The presentation, titled “LB-102 displays superior dopamine receptor occupancy compared to amisulpride in mouse and human positron emission tomography (PET) studies,” was presented at the ECNP ...

The primary objective was to evaluate the safety and tolerability of single ascending doses and multiple ascending IV doses of AK006 in healthy volunteers and to explore Siglec-6 receptor ...

The deal with MD Biosciences also includes receptor occupancy assays for CCR5 directed therapeutics, a promising target in the fight against COVID-19 and possibly other "cytokine storm" related ...

In the human brain the A1 adenosine receptor is the most abundant," said David Elmenhorst, MD, lead author of "Caffeine Occupancy of Human Cerebral A1 Adenosine Receptors: In Vivo Quantification ...

The presentation, titled “LB-102 displays superior dopamine receptor occupancy compared to amisulpride in mouse and human positron emission tomography (PET) studies,” was presented at the ECNP by ...