IgA nephropathy (Berger’s disease) is a chronic kidney disease that occurs when immunoglobulin A (IgA) deposits build up in the kidneys. It can cause blood in the urine, among other symptoms ...

Atrasentan is approved for proteinuria reduction in primary IgA nephropathy, a condition risking kidney failure. The phase 3 ALIGN study showed atrasentan reduced proteinuria by 36.1% compared to ...