The assembly of a Human Heart Cell Atlas is key given that cardiovascular ... drug targets as well as drug side effects. It leverages single-cell profiles and the 19 million drug-target ...

“The advent of single-cell sequencing has really revolutionized ... Christine Seidman said the heart cell atlas could also help engineers create artificial hearts for transplantation.

It leverages single-cell profiles and the 19 million ... a Coordinator of the Human Cell Atlas Heart BioNetwork and a lead author, said: "We often don't fully know what impact a new treatment ...

Using recent single-cell RNA sequencing techniques ... in mice with a genetic mutation that causes congenital heart defects in humans. “The study provides both a temporal and spatial atlas that plots ...

The most comprehensive cell "atlas" of the developing human ... MERFISH technology to study the human developing heart with spatially resolved single cell resolution," Zhu told Live Science ...

as well as identify candidate biomarkers to prevent heart attacks and strokes and improve patient outcomes. "We plan to extend this single-cell atlas with future iterations to include additional ...

To address this, the researchers created a reference atlas of human hematopoiesis using single-cell RNA sequencing data from 263,519 cells enriched for hematopoietic stem and progenitor cells. The ...

In the study, "Single-cell Transcriptional Atlas of Human Hematopoiesis Reveals Genetic and Hierarchy-Based Determinants of Aberrant AML Differentiation," published in Blood Cancer Discovery ...

The researchers constructed the largest single-cell atlas of the human kidney to date ... of Health Common Fund Programs; National Heart, Lung and Blood Institute; and the National Institute ...

as well as identifying candidate biomarkers to prevent heart attacks and strokes and improve patient outcomes. “We plan to extend this single-cell atlas with future iterations to include ...