New research from scientists at Cleveland Clinic’s Genome Center and their collaborators at other institutions describes a pathway that human herpes simplex-1 (HSV-1) can use to contribute to th ...

Over 30 years ago, researchers discovered a greater prevalence of human simplex virus type 1 (HSV-1) DNA in the brains of individuals who died from AD as compared to healthy individuals.

Researchers from Cleveland Clinic's Genome Center have outlined the pathway human herpes simplex virus-1 (HSV1) can use to contribute to Alzheimer's disease in aging brains. In a report published ...

HSV-1 is a large virus that infects the mucous ... The virus is composed of three layers—a capsid that contains the viral DNA, a protein layer called the tegument and an outer envelope that ...

The HSVs are part of a large family of DNA viruses, of which eight are known to be infectious in humans. Both HSV types 1 (HSV-1) and 2 (HSV-2) are transmitted across epithelial mucosal cells as ...

HSV-2 has been isolated from normal human sacral ganglia, [28] but the physical state of HSV-2 DNA and HSV-2 gene expression in latently infected human ganglia have not been studied nearly as ...

In 2009, HSV DNA was discovered inside amyloid plaques in the brains of those with Alzheimer’s. It is not only HSV-1 that has been connected to Alzheimer’s disease; other herpesviruses have also been ...

Researchers from Cleveland Clinic’s Genome Center outlined the pathway human herpes simplex virus-1 (HSV1) can use to contribute to Alzheimer’s disease in aging brains. In a report published ...