Degradation of the glycocalyx in response to endothelial activation can lead to albuminuria and subsequent renal and vascular inflammation, thus providing a pathophysiological framework for the ...

It is based on nanoparticles that mimic a special carbohydrate layer (glycocalyx) located on inflamed bowel cells, and which trigger anti-inflammatory effects in the diseased sites in the intestine.

One of the ways that cancer cells hide from the body’s immune system is by forming a thin surface barrier called the glycocalyx. In a new study, researchers examined the material properties of ...

These age-related changes to the glycocalyx weaken the blood-brain barrier, Shi found. As the barrier becomes leaky with age, harmful molecules can infiltrate the brain, potentially fueling ...

The starting point of their approach was the glycocalyx, a carbohydrate-rich layer that coats the cells on the surface of the intestine. Beneficial gut bacteria, which have their own matching ...

“The glycocalyx is like a forest,” Shi explains ... potentially fueling inflammation, cognitive decline, and neurodegenerative diseases. “This work lays the foundation for a new field ...

A recent study published in the journal Nature showed that the dysregulation of the brain endothelial glycocalyx layer impairs the blood-brain barrier (BBB) in disease and aging. The BBB forms a ...

The funding from this R35 grant will support the continued development of her research program for studying endothelial damage and organ inflammation after traumatic injury. Richter will lead the ...

CHATTANOOGA, TN / ACCESSWIRE / January 4, 2023 / BioRegenx, Inc. which has entered into a Definitive Agreement to merge with Findit, Inc, and its subsidiary Microvascular Health Solutions, LLC ...

while those with the least healthy microascularization experienced the most severe side effects The research team utilized the Glycocalyx Research Institute’s innovative GlycoCheck™ imaging ...

Cancer cells often form the glycocalyx with high levels of cell-surface mucins, which are thought to help protect the cancer cell from immune cell attack. However, a physical understanding of this ...