Leucovorin is turned into folic acid in your body. Folic acid can protect your healthy cells from the effects of high-dose methotrexate. When leucovorin is used for cancer, it can make certain ...

Methotrexate is a folic acid antagonist. It works by inhibiting the synthesis of purines and pyrimides and therefore interfering with DNA synthesis. Methotrexate affects rapidly dividing cells and ...

Medically reviewed by Ashley Baumohl, RD People with Crohn's disease are at an increased risk of certain nutrient ...

Folic acid can protect your healthy cells from the effects of high-dose methotrexate. When levoleucovorin is used for cancer, it can make certain chemotherapies work better to target and kill the ...