Fibroblasts play a central role in maintaining healthy tissue structures, as well as in the development and progression of ...

The heterogeneity of fibroblasts is key to developing targeted therapies in regenerative medicine and in the treatment of ...

During fibrosis, fibroblasts — connective tissue cells that synthesize the extracellular matrix — “become somehow dysregulated, either by injury or by mutation,” he added. “These fibroblast cells ...

Fibroblasts play a central role in maintaining healthy tissue structures, as well as in the development and progression of diseases. For a long time, these specialized connective tissue cells were ...

identifying a multipotent fibroblast progenitor in the fascia— the deepest connective tissue layer of the skin. These CD201+ fascia progenitors control how quickly wounds heal by making ...

Researchers have now developed an immunotherapy that specifically targets the cause -- activated fibroblasts -- while leaving normal connective tissue cells unharmed. If this approach is also ...

Dear Dr. Roach: In my 40s, I developed lumps in the palm of my hands. I was diagnosed with Dupuytren’s contracture and underwent hand surgery to correct the condition. I also noticed similar ...

“In animals, we were able to trigger an immune response similar to that to a vaccination, in which the activated connective tissue cells were destroyed while the resting fibroblasts were left ...