Of these cases, a significantly higher risk of serious adverse reactions was linked to ester-based anesthetics (odds ratio [OR]: 3.86, 95% confidence interval [CI]: 2.77 to 5.39) and a lower risk of ...

Dermatitis. 2010;21(3):176-177. Local anesthetics are widely used drugs. We present a case of allergic contact dermatitis from cinchocaine (dibucaine) and benzocaine in perianal medicaments.

Local anesthetics are classified into two main groups based on the chemical structure of the intermediate chain: one being an amide group and the other being an ester group. This type of ...

The commonly used drugs are amides like lignocaine, prilocaine, and bupivacaine. The other group is esters like cocaine, procaine, and amethocaine. Local anesthesia wears off quickly. WebMD states ...

All patients had positive reactions to prilocaine and negative reactions to lidocaine and therefore had no cross-reactions between the two local anesthetics ... with amide anesthetics are uncommon ...

However, an anesthetic from the ester group could be used as an alternative if a patient is allergic to amide anesthetics ... According to the article, using a local injection of 1% ...