Increased activity in a specific biological pathway may explain why many patients with a deadly form of skin cancer do not ...

that activation of the epidermal growth factor receptor (EGFR)-mediated signaling pathway is involved in lenvatinib resistance in thyroid cancer cells. Although thyroid cancer is the most common ...

In a recent study, researchers have uncovered the biological trigger behind the dangerous immune-related adverse events ...

Increased activity in a specific biological pathway may explain why many patients with a deadly form of skin cancer do not ...

In a recent study, researchers have uncovered the biological trigger behind the dangerous immune-related adverse events (irAEs) that occur when the ...

KRAS mutations are among the most common genetic alterations in cancer and are considered particularly difficult to treat. In colon cancer, the second most common cause of cancer death, such mutations ...

No writing assistance was utilized in the production of this manuscript. Ligand-mediated EGF receptor (EGFR) targeting of nanovehicles is an effective way for cancer cell-selective delivery of ...

EGFR signaling was measured by western immunoblotting and receptor internalization was evaluated by fluorescent microscopy (pEGFR (pY1068) colocalization with early endosome marker EEA1).