After decades of antipsychotic drugs, a new FDA-approved treatment for schizophrenia targets a different brain system—with ...

New research identifies a promising strategy for correcting dopamine imbalances in the brain using a drug that blocks kappa ...

These receptors and the cells that express them mediate opposite approach/avoidance responses, and are differentially impacted by dopamine transmission in that region of the brain.

Levodopa — which is converted into dopamine in the brain and targets the D2/D3/D4 dopamine receptors — has been linked to side effects including sleep disorders, hallucinations, impulse ...

But all opioid receptors are not the same. In the current study, the researchers targeted KOR, a subtype of opioid receptor that when activated can decrease synaptic dopamine levels by decreasing ...

Now, new research suggests the drug’s effectiveness is less about the amount of dopamine it produces and more about the number and type of receptors that respond to it. Conditions where a person ...

Researchers have discovered distinct roles for two dopamine receptors located on nerve cells within the portion of the brain that controls approach vs. avoidance behavior. Mount Sinai researchers ...

Levodopa — which is converted into dopamine in the brain and targets the D2/D3/D4 dopamine receptors — has been linked to side effects including sleep disorders, hallucinations, impulse ...

Citation: Discovery of dopamine receptors in overlooked brain region sheds light on complex circuitry for anxiety and depression (2025, May 7) retrieved 6 June 2025 from https://medicalxpress.com ...