Reported adverse effects of docetaxel include hypersensitivity reactions (presenting as flushing, skin reactions, hypotension and bronchospasm), bone marrow suppression (neutropenia, thrombocytopenia, ...

Docetaxel is a chemotherapy drug that is used ... neutropenia, allergic reaction, fluid retention, edema, dizziness, hair loss, diarrhea, cramping and dysphagia, compared with those who took ...

For each patient, the investigators read the nursing note to look for evidence of any documented adverse effect that occurred after beginning docetaxel or paclitaxel infusion. Because of the high ...

When should Docetaxel not be taken? (Contraindications) Contraindicated in patients with previous severe hypersensitivity reaction to this drug, the solvent or polysorbate 80, severe decrease in ...

These results from the TROPION-Lung01 Phase III trial, which compared the standard of care in second-line docetaxel, a type of chemotherapy, with Dato-DXd, an antibody drug conjugate, in patients ...

hypersensitivity reaction, and pulmonary infiltrates (fatal in two patients). Late toxicity of esophageal stricture occurred in five patients. Esophagitis and neutropenia are the dose-limiting ...

multicenter study evaluating tusamitamab ravtansine (a CEACAM5-directed antibody-drug conjugate (ADC) with cytotoxic payload DM4/ravtansine) versus docetaxel in patients with advanced non-squamous ...

The grade three adverse events in the study were attributed to the hematological adverse reactions due to docetaxel use, which were controlled with leukopoietic agents. Overall, the findings from ...

Treatment with datopotamab deruxtecan (Dato-DXd), a novel Trop-2 directed antibody-drug conjugate ... or death compared to patients treated with docetaxel. "While there was an overall reduction ...