Cystic fibrosis (CF) is a serious disease that runs in families. It’s caused by a gene that doesn’t work ... There, doctors look for high levels of a chemical called IRT, which may mean ...

People with CF typically have higher levels of chloride in their sweat. Genetic testing can determine if a person has cystic fibrosis (CF) or carries gene mutations that cause it. Genetic testing ...

In their 2019 paper, Liu’s team used prime editing to alter the gene mutations causing sickle cell disease ... a lung biologist and research director at Cystic Fibrosis Trust, who was not involved in ...

The protein DNase1 is one of the oldest biological agents in history. It has been on the market since 1958 and is now used, ...

People with CF have higher levels of chloride ... High amounts of salt will confirm CF. Cystic fibrosis is caused by a faulty gene that’s passed down from both parents. You can carry this ...

Cystic fibrosis is an inherited lifelong disease that gets worse over time. It is estimated to affect 105,000 people worldwide. There are more than 2,000 known mutations in the CFTR gene, which lead ...

People with cystic fibrosis ... incorrect structure. This prevents CFTR from moving to the cell membrane, so it’s never able to complete its function. Because the protein and gene share a ...

An inhalable medicine with the potential to improve lung disease in people with cystic fibrosis ... known mutations in the CFTR gene, which lead to different levels of the severity of the disease.

Research shows Black cystic fibrosis patients are more likely than their white counterparts to be among the 10% who don’t benefit from modulator therapies. Can a gene therapy work no matter the ...

ReCode Therapeutics is set to secure up to $15m in additional funding from the Cystic Fibrosis Foundation to enhance its gene correction research programme. The initiative, conducted in ...

This resulted in a high level of gene editing, which boosted levels of the protein made from the cystic fibrosis gene by 5.5-fold, which was enough to restore half of the normal function of the ...