Succinyl-CoA:3-ketoacid CoA transferase (SCOT; locus symbol OXCT; E.C. 2.8.3.5) is the main determinant of the ketolytic capacity of tissues. Hereditary SCOT deficiency causes episodic ketoacidosis.

OXC and the class III CoA-transferase formyl-CoA:oxalate CoA-transferase (FCOCT) are widespread among bacteria, including many that have no apparent ability to degrade or to resist external oxalate.

Panel A shows the effects of lipid excess. Ceramide synthesis begins with the condensation of serine and palmitoyl CoA by serine palmitoyl transferase 1 (SPT1), subsequent reduction by 3 ...

Asthma is currently defined by reversible airflow obstruction, airway hyperreactivity, and airway inflammation. Of the three diagnostic criteria, asthma symptoms track most closely with airway ...