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Succinyl-CoA:3-ketoacid CoA transferase (SCOT; locus symbol OXCT; E.C. 2.8.3.5) is the main determinant of the ketolytic capacity of tissues. Hereditary SCOT deficiency causes episodic ketoacidosis.
OXC and the class III CoA-transferase formyl-CoA:oxalate CoA-transferase (FCOCT) are widespread among bacteria, including many that have no apparent ability to degrade or to resist external oxalate.
Once in the cell, succinyl‐CoA: phthalate CoA transferase (SPT) converts PA to the unstable phthaloyl‐CoA. The second step in anaerobic PA degradation is its decarboxylation, catalyzed by ...
Panel A shows the effects of lipid excess. Ceramide synthesis begins with the condensation of serine and palmitoyl CoA by serine palmitoyl transferase 1 (SPT1), subsequent reduction by 3 ...