By mimicking epinephrine, beta-agonists can bind to adrenergic receptors ... Although SABAs and LABAs have similar mechanisms of action, they differ by their half-life (the time it takes to ...

We also saw that overexpression of only D2 receptors on beta cells exerted an inhibitory and toxic effect and abolished insulin secretion in beta-cells. This gave us a clue to the mechanism of ...

The company reported that its THR-beta agonist product ... NASH and support prior research indicating THR-β as an important mechanism of action for the treatment of this debilitating disease.” ...

VK2809 is an orally available, tissue and receptor-subtype selective agonist of the thyroid hormone beta receptor (TRβ ... lipoprotein levels via multiple mechanisms, including increasing ...

and glucagon Receptors, improves markers of pancreatic beta-cell function and insulin sensitivity" ADA 2024; 266-OR.

G protein-coupled receptors (GPCRs) are essential for cell ... thus greatly expanding knowledge of the mechanism underlying arrestin-mediated regulation of GPCR signal transduction.

Although beta-2 agonists have been associated with a reduced risk of Parkinson's disease in some previous epidemiological studies, this association was not found in a recent register-based study ...