The amino acid sequence of a protein or peptide is useful information to understand the protein or peptide, identify it in a sample and categorize its post-translational modifications.

The simplest way to decipher the code would be to start with an mRNA molecule of known sequence, use it to direct the synthesis of a protein, and then determine the amino acid sequence of the ...

While initial screening reveals the composition of the samples, next-generation protein sequencing technology facilitates a comprehensive interrogation of amino acid variations, modifications ...

A cutting-edge technique for analyzing fossil tooth enamel is revealing remarkable new information about 2 million-year-old human relatives.

By removing one amino acid after another and repeating the tagging and imaging steps, researchers can record a sequence of amino acids for each peptide in a sample of millions simultaneously.

Biochemists were constantly pushing the limits of technology to couple, cleave, extract, and sequence peptides with better sensitivity. Pehr Edman, in 1950, developed a chemical degradation process ...

Although the rational protein design approach offers an increased possibility of beneficial alterations, it is not easy to accurately predict the sequence-structure-function relationship, particularly ...