To investigate the effects of ethanol on the expression of AMP-activated protein kinase (AMPK), myocyte enhancer factor 2 (MEF2) and glucose transporter 4 (GLUT4), all of which are involved in the ...

The roles of AMP-activated protein kinase (AMPK) and myocyte enhancer factor 2 isoforms (MEF2A, D) as mediators of the effects of ethanol on glucose transporter 4 (GLUT4) expression are unclear ...

Creatine administration that increases AMPK activity by decreasing the phosphocreatine-to-creatine ratio [34] may, thus, explain the increase in GLUT4 protein content in the creatine group.

In normal myocytes, insulin treatment activates glucose uptake to the muscle by promoting the cell surface delivery of cytoplasmic storage vesicles that contain the glucose transporter GLUT4. Like ...

Its pipeline includes first-in-class oral therapies that target the GLP-1 receptor and isoform-specific/selective AMPK signaling, with programs focused on obesity, metabolic dysfunction, age ...

AMPK is normally a tumour suppressor. But once cancer arises, AMPK becomes a tumour promoter, enhancing the survival of cancer cells. Understanding this could help create drugs that inhibit AMPK.

The addition of 2 mmol/L AICAR, a known stimulator of AMPK and glucose transport in these and other cells, to resveratrol-treated Clone 9 cells stimulated AMPK phosphorylation but had no effect on ...

Ginseng is a natural remedy for diabetes management, helping with blood sugar control, insulin sensitivity, and glucose metabolism. Its health benefits support type 2 diabetes prevention and diabetic ...

This study concludes that activation of the PPARβ/δ-AMPK pathway is an effective strategy to slow the development of liver fibrosis.

Nimbus eligible to receive up to $496 million, inclusive of research funding and potential milestone payments, in addition to royalties on net sales AMPK activation is a promising strategy to ...